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UnderGraduate Courses
General Pharmacology and Toxicology
The basic educational activity of the department of Pharmacology is the teaching of the
subject General Pharmacology and Toxicology. It includes the mechanisms of drug action, their
properties and medical applications. The subject of Pharmacology is divided for educational
reasons into the following two semesters:
PHARMACOLOGY I (5th semester, 52 teaching hours)
General principles of Pharmacology (16 hrs)
Autonomic nervous system - Smooth muscles (18 hrs)
Drugs of CNS - Analgesics (18 hrs)
PHARMACOLOGY II (6th semester, 50 teaching hours)
Cardiovascular stimulating drugs - Antidysrythmic drugs (4 hrs)
Respiratory and gastrointestinal system: Drugs (4 hrs)
Drugs of Anaemias, Vitamins, Hormones (18 hrs)
Chemotherapy of infectious and neoplastic diseases (18 hrs)
Poisoning, Antidotes (6 hrs)
Practical Exercises
During the 5th semester, demonstrative but also practical exercises regarding items of
Pharmacology covers several topics. By that mean, students in different groups participate in
exercise-courses, like:
Teratogenesis
Drug Interactions (antagonism-synagonism)
Autonomic Nervous System (Langendorff heart preparation
Nerve Ending
Anti-inflammatory and Analgesics Drugs
Drugs of CNS
The existence of this part of the educational procedure has a main target the establishment
of the information by the students.
Selective Subjects
The teaching of selective subjects consists of practical courses, seminars or demonstrations.
DEVELOPMENT OF NEW PRODUCTS Methodology of Experiments in Pharmacology
and Toxicology (5th semester, 20 teaching hours)
Experimental animals
In vitro and in vivo methods of drug toxicity evaluation
Methods in Biochemical Pharmacology
Plasma drug levels
Methodology in Neuropharmacology
Biotechnology in the development of new drugs
Clinical testing of new drugs (ethical and legal principles)
NARCOTICS The Pharmacology and Toxicology of Drugs of Abuse (5th semester, 20
teaching hours)
Terminology
Opioid Alkaloids
Depressants
Psychostimalants
Cannabis
Smoke
MOLECULAR PHARMACOLOGY (6th semester, 20 teaching hours)
The theory of receptors
Drugs and CNS receptors
Steroid hormone receptors
Drugs and myocardial receptor
Receptors of pathogenic microorganisms
Cancer cell receptors
CLINICAL PHARMACOLOGY (6th semester, 20 teaching hours)
Anaesthetics
Treatment of myocardial infarct
Ingestive
Antibiotics in surgery
Basic principles of anticancer therapy
Drugs and fertility
Treatment of pain
Drugs and kidney
TOXICOLOGY OF DRUGS (5th semester, 20 teaching hours)
Principles of Toxicology
Occupational Toxicology
Treatment of Poisoned Patients
Poisons and Antidotes
Beside seminars, the students undertake to prepare and present a review on a specific issue.
Graduate courses - Post-graduate Seminars
There is a series of postgraduate lessons on General Pharmacology and Toxicology
presented by staff members, but also by members of other Departments of Medical School.
In parallel, other series of research seminars on different scientific fields regarding Pharmaco-
Toxicology are active; the seminars presented by staff members and, mainly by the postgraduate
students.
The participation of under-graduate students in these activities is possible and welcome on
condition that they have passed the examinations of Pharmacology I and Pharmacology II.
Post-graduate Research Projects
The policy of the Department in the area of research is consistent to the principles of the
academic freedom. Despite all these, because of the limited economic sources which are essential
for the supplying of expensive equipment, researchers have to be focused on specific disciplines
which allow the cooperation and the better development of the scientific equipment and human
potential.
The research disciplines of the Department are the followings:
Drug Metabolism in the liver and in other extra-hepatic tissues.
Mechanisms of cell resistance against oxidative factors and the role of several biochemical
parameters in the elimination of free radicals.
Hormonal factors of homeostasis which affect the maturation and discrimination of the liver
cells, regarding mechanisms of drug metabolism.
Studies in Applied Pharmacology; the main subject is the further investigation of several
pharmaceutical products. Different clinical and pharmacokinetic trials which take place in
cooperation with colleagues working at the University Hospital, belong to this category.