Medical pharmacology curriculum at the 1st Faculty of Medicine, Charles University, Prague.

Contact: Prof. Hassan Farghali, D.Sc. Professor of pharmacology, Chairman. Institute of Pharmacology, 1st Faculty of Medicine, Charles University, Albertov 4, 128 00 Prague 2, Czech Republic. Tel + 420 2 293254, fax + 420 2 293254, email hfarg(lf1.cuni.cz .

1. Information on
Pharmacology lectures and seminars
These lectures and seminars are intended for the 3rd year medical students of this school. A reduced version of the lectures are delivered to the bachelor degree students of various types of nursery studies and as a special course for students of the faculty of education that will teach young students who have some physical or mental defects. Indeed, at this institute students from the faculty of medicine, department of dentistry, four types of bachelor degree nursing students, and the so-called specially oriented students from the faculty of education at Prague Charles University are receiving their pharmacology education. In addition, 8 postgraduate students are preparing for their Ph.D. degree in pharmacology within the university program of biomedical sciences.
Teaching medical students (medicine and dentistry) takes place during two semesters. Each semester terminates with a credit. After the two credits the student should pass an examination of essay type of questions. Teaching for the other types of students takes place in one semester that terminates with credit and an examination.

Lectures (winter semester)
1. Introduction, aim of teaching of pharmacology, development of new drug
2. Pharmacokinetics I, basic principles, absorption, distribution
3. Pharmacokinetics II, elimination and clinical aspects
4. Pharmacodynamics I, mechanisms of drug effect
5. Pharmacodynamics II, quantitative relationships of receptor-ligand complex
6. Side effects of drugs, principles of gene therapy
7. Drugs affecting autonomic nervous system , general principles
8. Drugs affecting autonomic nervous system, sympathomimetics and sympatholytics
9. Drugs affecting autonomic nervous, parasympathomimetic and parasympatholytics
10. Local anesthetics and peripheral skeletal muscle relaxants
11. Introduction to CNS pharmacology, general anesthetics
12. Hypnotic, antiepileptics
13. Psychopharmacology, classification of psychoacting drugs, neuroleptics
14. Drugs in depression and mania, psychostimulants
15. Pharmacology of pain, opoioid analgesics

Lectures: (summer semester)
1. Nonsteroidal antiinflammatory drugs (NSAID) and other anti-inflammatory drugs
2. Diuretics
3. Cardiac glycosides and other drugs used in congestive heart failure and ACE inhibitors
4. Antiarrhythmic drugs, antianginal drugs
5. Drugs affecting blood coagulation, drug treatment of anemia
6. Pharmacotherapy of bronchial asthma, and drug treatment of some allergic conditions
7. Antimicrobial drugs (mechanisms of action, overview of important groups)
8. Antimicrobial drugs (b-lactam antibiotics, macrolides, lincosamides, aminoglycosides and tetracyclines)
9. Antimycotic drugs, chemotherapy of some diseases
10. Hormones and vitamins
11. Chemotherapy and hormonal treatment of cancer
12. Introduction to immunopharmacology
13. Locally used drugs
14. Oculopharmacology
15. Selected topics (e.g. important drug interactions, geriatric pharmacology)

Seminars: (winter semester)
1. Introduction to prescription writing, drug libraries
2. Pharmaceutical formulations and prescription writing (part I)
3. Pharmaceutical formulations and prescription writing (part II)
4. Pharmacokinetics (clinical applications and solving common problems part I)
5. Pharmacokinetics (clinical applications and solving common problems part II)
6. Test on pharmacokinetics (MSQ)
7. Drug interactions, drug intoxication
8. Autacoiods and and significance in pharmacotherapy
9. Test on prescription writing
10. Histamine, antihistaminicand therapeutic uses
11. Test on basic principles of pharmacology
12. Pharmacologic management of parkinsonism
13. Alcohols, drug addiction
14. Test on autonomic drugs (MCQ)
15. Antianexiety, pychostimulants and nootropic drugs, CREDIT I

Seminars: (summer semester)
1. Introduction of pharmaceutical industry in Czech Republic to the medical students
2. Agents affecting bone mineral homeostasis, osteoporosis
3. Test on drugs acting in CNS (MCQ on hypnotics, antiepileptics, general anaesthetics, opiates)
4. Drugs used in hyperlipidemias
5. Psychopharmacology, an overview (MCQ test on the subject)
6. Drugs used in the teatment of respiratory system diseases (bronchodilators,
7. expectorants, antitussive agents)
8. Repetition of cardiovascular drugs, mechanisms of action, classification, (MCQ test on the subject)
9. Drugs used in GIT diseases (antacids, antiulcers, antiemetics, and spasmolytics)
10. Drugs during pregnancy and lactation (tocolytics, uterotonics, an overview of adverse effects of drugs during pregnancy)
11. Drugs affecting mycobacterial, and viral infections
12. Antimicrobial drugs, an overview (MCQ test on the subject)
13. Sex hormones, contraception
14. Drugs used in the treatment of diabetes mellitus and thyroid gland diseases
Repetition of chapter(s) of special interest according to the studentsþrequest, CREDIT II

Information on new trends in pharmacology curriculum at the 1st Faculty of Medicine, Charles University, Prague

The new trend in pharmacology teaching at this institute includes the addition of new lectures in immunopharmacology, gene therapy and ocular pharmacology.

Students of the final year of the Faculty of Education at Charles University, the so-called specially oriented students are receiving pharmacology education at this institute. The reason for this is that those students will be the future teachers for pupils or students who are mentally or physically abnormal. The latter young people usually are under drug treatment. So it is advocated that their teachers should have basic knowledge in pharmacology and some related subjects.

At present we are preparing a computer network for studentsþ pharmacology teaching at this institute. The goal is to enable them to use available pharmacology software for teaching and interactive learning.

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