VIth and VII-th semesters - Lectures=45hr, Tutorials=75hrs
VIIIth and IXth semesters - Seminars = 15 hrs; tutorials = 30 hrs.
LECTURES or TUTORIALS
Program of lectures on medical pharmacology during VI- and VII-th semesters
PRINCIPLES OF DRUG ACTION
Drug absorption and distribution
Drug metabolism and excretion
Pharmacokinetics and pharmacodynamics
Molecular basis of drug action
Factors that modify drug effects and drug interactions
Ionotropic and G-protein coupled receptors
Receptor controlled generation of secondary messengers (G-protein, second messengers,
transducers)
G protein-coupled receptors
Neurotransmitters and other chemical signalling agents
LOCAL HORMONES AND AUTACOIDS
COX-1 and 2 inhibitors
Inhibitors of lipooxygenase and antagonists of the leucotriene receptors
Angiotensin converting enzyme inhibitors and A1/A2 receptor antagonists
PERIPHERAL AUTONOMIC CHOLINERGIC MECHANISMS
he review and overview of the autonomic system pharmacology
Nicotinic receptors, ganglionic blocking drugs, neuromuscular blocking agents
Muscarinic receptor agonists and antagonists
PERIPHERAL ADRENERGIC MECHANISMS
Alpha and beta-adrenoceptor agonists
Alpha and beta-adrenoceptor antagonists
HUMORAL MECHANISMS IN THE CENTRAL NERVOUS SYSTEM
The pharmacotherapy of pain
CARDIOVASCULAR PHARMACOLOGY
Ca2+ and Ca2+-channel agonists and antagonists
Angiotensin converting enzyme (ACE) inhibitors
Antianginal drugs
Antihypertensive drugs
Inotropic agents and the treatment of heart failure
Antiarrhythmic drugs
Anticoagulants
Antiplatelet agents as antithrombotic drugs
Drugs used to treat angina pectoris
DRUGS AFFECTING THE RESPIRATORY TRACT FUNCTION
Bronchodilators and asthma
Histamines and antihistamines
HUMORAL MECHANISMS IN THE CENTRAL NERVOUS SYSTEM
Central nervous system stimulants
Anxiolytics, sedative-hypnotics
Antipsychotic drugs
Drugs used to treat affective disorders
Selective serotonin reuptake inhibitors
Renal physiology and the sites of action of diuretics
Drugs affecting the gastrointestinal tract
The choice of antibiotic therapy
Non-steroidal anti-inflammatory drugs (NSAIDS) and slow acting anti-rheumatic drugs
(SAARDS)
Antimicrobials in pregnancy
The overview of cancer chemotherapy
Disorders of lipids and lipoproteins-classification and pharmacotherapy
Anemia caused by vitamin deficiency
Titles of the tutorials and seminars during VII- and VIII-th semesters:
1a) Antithrombotic agents
Anticoagulants
Anticoagulant antagonists
Antiplatelet agents
Thrombolytic therapy
Antidotes to thrmbolytic therapy
1b) Drugs affecting the cardiovascular system function
Inotropic agents
Pharmacology of the ischaemic heart disease
Antihypertensive therapy
Disorders of arteries and veins
2a) Drugs affecting the function of the respiratory tract
Respiratory stimulants
Drugs used in the treatment of asthma
2b) Drugs affecting the function of the alimentary tract
Pharmacotherapy of peptic ulcer disease
Constipation and laxatives
Diarrhea and antidiarrheal drugs
3a) Drugs affecting renal and urinary tract function
3b) chemotherapy of viral, bacterial and fungal infections
4a) Central nervous system
General and local anaesthetics
Neuromuscular blocking agents
Drugs used to relieve pain
Drugs used in the treatment of Parkinson's disease
Epilepsy
4b) Psychotropic drugs
Anxiolytics, sedative-hypnotics
Drugs to treat mood disorders
Drugs to treat psychoses
5) Drugs affecting the endocrine system
6) Pharmacokinetic and pharmacodynamic interactions
7a) Angiotensin converting enzyme inhibitors
7b) Angiotensin II receptor antagonists (A-1 and A-2 receptors)
8) Basic and clinical pharmacology of nitric oxide
9) Antimicrobial agents I
10) Antimicrobial agents II
11 Chemotherapy and immunotherapy of neoplastic disease
12) Drugs and the immune system
13) Systemic hemostasis. Drugs that affect coagulation
14) Metabolism and nutrition